Cortical morphometry in narcolepsy with cataplexy

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Cortical morphometry in narcolepsy with cataplexy.

The sleep-wake disorder narcolepsy with cataplexy is associated with the loss of hypocretin-(orexin-) producing neurons in the lateral hypothalamus. Several studies have reported abnormal cerebral activation in patients with narcolepsy with cataplexy. It remains unclear, however, whether these functional changes are related to structural alterations, particularly at the cortical level. To quant...

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Narcolepsy with cataplexy in monozygotic twins

INTRODUCTION This paper describes narcolepsy with cataplexy in two monozygotic twin sisters. OBJECTIVE To clinically illustrate the involvement of neurological, genetic and immunologic systems in narcolepsy. MATERIAL AND METHODS We performed a restropective study of these patients that were followed in the sleep medicine ambulatory clinic of the Faculdade de Medicina de Ribeirao Preto. RE...

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Narcolepsy with cataplexy in early childhood.

Narcolepsy is a rare neurologic sleep disorder with morbidity associated with functional impairment and frequent delay in diagnosis. Symptoms typically manifest in adolescence or early adulthood, but diagnosis of narcolepsy has been reported in early childhood. Diagnosis rates are as low as 50% of the total population of patients with narcolepsy and are delayed as much as 10 years after disease...

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Low Vitamin D in Narcolepsy with Cataplexy

BACKGROUND Narcolepsy with cataplexy (NC) is currently thought to be an autoimmune-mediated disorder in which environmental risk factors make a significant contribution to its development. It was proposed that vitamin D deficiency plays a role in autoimmune diseases. Here we investigated whether NC can be associated with 25-hydroxyvitamin D (25(OH)D) level deficiency in patients with NC compare...

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Narcolepsy and Cataplexy

After hearing the punch line of the joke, the teenager falls to the floor, almost as if actually punched. She remains there, completely unable to move. She hears her parents reassure her friends that they need not worry about her because she will be all right in a few minutes. She is embarrassed and frustrated as the episode continues, and her friends begin to leave. They bid her goodbye, but s...

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ژورنال

عنوان ژورنال: Journal of Sleep Research

سال: 2012

ISSN: 0962-1105

DOI: 10.1111/j.1365-2869.2012.01000.x